Tyler Police have shut down all North and South bound traffic on Highway 155 South and County Road 1114, this is South of Loop 323.
They are asking drivers to use alternate routes.
The fire is located in the 12000 block of Highway 155 South.
Several fire departments across East Texas were called to help battle a fire on Highway 155 South in Tyler.
Fire fighters tell us a storage building and two other buildings are on fire.
Authorities have blocked off the area near the fire due to explosions.
CBS 19 has a crew on the scene and we'll have updates throughout the night.